Typical symptoms include weight loss, fever and night sweats, while physical examination often eveals asthenia, hepatomegaly, jaundice and scitis. bstructive jaundice may occur as a late anifestation of NHL resulting from encasement f the common bile duct by the tumor. Imaging tudies usually reveal a solitary mass in the liver lthough multiple masses may occur, albeit less requently. Primary lymphoma is usually hypoechoic or anechoic on US and hypodense on CT. On pre-contrast T2-weighted MR imaging, most lesions are homogeneously hyperintense with a SI that is comparable to or higher than that of the spleen.
This is radiology images of the T2-weighted image (a) reveals a giant hyperintense, sharply demarcated mass in e right liver lobe. Displacement of the portal vein (arrow) can be seen on the true FISP image (b). The lesion is homogeneously hypointense on the unenhanced T1-weighted image (c) and shows slight but homogeneous enhancement on T1-weighted fat sppressed dynamic images following the bolus injection of Gd-BOPTA (d-f). The tumor is again hypointense on T1-weighted fat suppressed (g), and T1-weighted (h) images acquired during the hepatobiliary phase after injection of Gd-BOPTA. Distinct tumor margins are again depicted clearly.
Primary hepatic large cell lymphoma
4/ 5Oleh Habifa