Biochemical analysis
In many pancreatic diseases, the production of the digestive pancreatic enzymes is compromised, either by obstruction of the duct draining the pancreas
or by destruction of the pancreatic cells which produce the enzymes. This can result in malabsorption of food and/or diarrhoea.
The pancreas produces digestive enzymes, amylase, lipase and peptidase, which occur in trace amounts in the blood. If the pancreas is damaged or inflamed, the resulting release of enzymes into the blood stream causes an increase in the serum amylase and lipase levels. The enzymes also pass from the blood stream into the urine and therefore urinalysis can also contribute to the diagnosis.
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