— Both HSV1 and 2 are commonly prevalent in Indian population. (Mixed=83%, HSV1=10%, HSV2=1%) 
— HSV2 along with TORCH agents are major causes of neonatal encephalitis.
— Infections result from maternal birth canal or transplacental spread
— Unlike HSV1, HSV2 infection in neonates is diffuse.
— Imaging findings are nonspecific.
— CT scans in early disease may be negative or show subtle areas of low density
— Conventional MR and DWI show lesions better.
— Lesions may be multifocal involving almost any area of brain or limited to temporal lobes brainstem and cerebellum.
— Watershed infarcts may be seen
— In-utero infections can result in microcephaly, encephalomalacia or calcification.
sOURCE )Vossough.2008. Neuroradiol 50:355
Axial T1WI MR shows diffuse cystic encephalomalacia and prominent CSF-containing spaces
Axial T2WI MR shows areas of high signal in frontal lobes WM due to acute H5V-2
abnormal mri brain HSV 1 AND HSV2