Ct Scan of the chest in case Smoking Related ILD (Interstitial Lung Disease) Interstitial Lung Disease


  1. • Respiratory bronchiolitis: (RB)

  2. • Respiratory bronchiolitis-interstitial lung disease (RB-ILD

  3. • Desquamative interstitial lung disease (DIP)


Smoking Related ILD RB

  • • Clinical : Cigarette smoke or equivalent, Asymptomatic

  • • Pathology: Peribronchiolar macrophages, Peribronchiolar fibrosis

  • • Imaging : Centrilobular nodules, Poorly defined 2-3 mm, Uper lobe predominance, Ground glass opacity, Bronchial wall thickening, Decreased attenuation, Emphysema, Air trapping, Reticulation


(Niewoehner, NEJM 1974 ; Remy-Jardin, Radiology 1993)

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Ct scan of Smoker’s ma


CT SCAN OF the chest in Smoking Related ILD (RB-ILD) Respiratory bronchiolitis-interstitial lung disease




  • Clinical: Cigarette smoke or equivalent, Dyspnea, Restrictive or mixed PFT’s, Good prognosis

  • Pathology: Peribronchiolar macrophages, Peribronchiolar fibrosis

  • Imaging : Centrilobular nodules Poorly defined 2-3 mm Uper lobe predominance, Ground glass opacity, Bronchial wall thickening, Decreased attenuation, Emphysema, Air trapping, Reticulation

  • (Meyers, Am Rev Respir Dis 1987 Park, J Comput Assist Tomogr 2002) crophages


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Ct scan of the chest Small centrilobular nodules with an upper lobe predominance in RB-ILD

CT SCAN CHEST OF Smoking Related ILD DIP (Desquamative interstitial lung disease)




  1. • Clinical: Cigarette smoke, 4th and 5th decade,Uncommon, 70% survival-10 years, Steroids

  2. • Pathology : Pigmented macrophages, Interstitial infiltrate, Plasma cells and eosinophils, Fibrosis

  3. • Imaging :   Ground glass: Symmetrical and Basal predominance and Reticulation : Cysts: Alveolar ducts, Bronchioles, Emphysematous spaces


(Carrington, NEJM 1978 ; Hartman, Radiology1993)

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ct scan of the chest Ground glass opacities in DIP

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