Ct Scan of the chest in case Smoking Related ILD (Interstitial Lung Disease) Interstitial Lung Disease

1. • Respiratory bronchiolitis: (RB)


2. • Respiratory bronchiolitis-interstitial lung disease (RB-ILD


3. • Desquamative interstitial lung disease (DIP)

Smoking Related ILD RB

• • Clinical : Cigarette smoke or equivalent, Asymptomatic


• • Pathology: Peribronchiolar macrophages, Peribronchiolar fibrosis


• • Imaging : Centrilobular nodules, Poorly defined 2-3 mm, Uper lobe predominance, Ground glass opacity, Bronchial wall thickening, Decreased attenuation, Emphysema, Air trapping, Reticulation

(Niewoehner, NEJM 1974 ; Remy-Jardin, Radiology 1993)

Ct scan of Smoker’s ma

CT SCAN OF the chest in Smoking Related ILD (RB-ILD) Respiratory bronchiolitis-interstitial lung disease

• Clinical: Cigarette smoke or equivalent, Dyspnea, Restrictive or mixed PFT’s, Good prognosis


• Pathology: Peribronchiolar macrophages, Peribronchiolar fibrosis


• Imaging : Centrilobular nodules Poorly defined 2-3 mm Uper lobe predominance, Ground glass opacity, Bronchial wall thickening, Decreased attenuation, Emphysema, Air trapping, Reticulation


• (Meyers, Am Rev Respir Dis 1987 Park, J Comput Assist Tomogr 2002) crophages

Ct scan of the chest Small centrilobular nodules with an upper lobe predominance in RB-ILD

CT SCAN CHEST OF Smoking Related ILD DIP (Desquamative interstitial lung disease)

1. • Clinical: Cigarette smoke, 4th and 5th decade,Uncommon, 70% survival-10 years, Steroids


2. • Pathology : Pigmented macrophages, Interstitial infiltrate, Plasma cells and eosinophils, Fibrosis


3. • Imaging :   Ground glass: Symmetrical and Basal predominance and Reticulation : Cysts: Alveolar ducts, Bronchioles, Emphysematous spaces

(Carrington, NEJM 1978 ; Hartman, Radiology1993)



ct scan of the chest Ground glass opacities in DIP

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