Acro-osteolysis can be understood by breaking down its components:
acro refers to the digits,
osteo refers to the bone
, and
lysis means to break down. In other words, terminal tuft erosions. While not very common, there is a differential for this. I like to think of it as when you see the bony finger tips being
PINCH(ed)
OF:
| Disease | Notes |
| P | Pyknodysostosis | associated with osteosclerosis and Wormian bones |
| I | Injury (thermal) |
|
| N | Neuropathic | diabetes, leprosy |
| C | Collagen vascular disease | scleroderma, Raynaud's phenomenon |
| H | Hyperparathyroidism | calcium, resorption |
|
|
|
| O | Other | Progeria, Polyvinyl chloride exposure |
| F | Familial | Hadju-Cheney disease |
Note how the terminal tufts appear in the image above. They should be more uniform without the erosions seen in the image above.
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