Gadolinium For Radiologist
This is a supplement to our previous post on MRI contrast media, submitted by Dr MGK Murthy.
- Chemical element with Atomic No 64 in periodic table in lanthanide series
- Atomic weight of 157.25g.mol_1
- malleable
- world produces pure gadolinium of appx 400 tonnes
- because of nature of high absorption of neutrons used in nuclear medicine
- because of paramagentic properties used in MRI for contrast after chelating, as free gadolinum is toxic
- If the patient has normal renal function, use of any gadolinium compound makes no difference as renal excretion gets it out of the body
- If the patient has moderate renal dysfunction, use of less dose, interval of at least 7days between repeat doses and preferable use of macromolecule varities would help
- If the patient has severe renal dysfunction, use of macromolecules would be advised
- In extremes of age and lactating mothers , macromolecules is recommended
- If the patient has Calculated GFR of < 30ml/mt/1.73m2, Gadolinuim use is prohibited
- In pregnancy , Gadolinium is contraindicated
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